So many of us have been moved to mail a box of food, clothes or toys after hearing about a natural disaster or tragic event. But humanitarian logistics expert Dale Herzog says: Ask yourself three questions before sending another box into the chaos.

Half the vaccines that are manufactured each year don’t make it to their destination, getting lost or damaged along the way between manufacturer and remote health clinics. That means that each year, 1.5 million children in the developing world die needlessly. Neuroscientist and TED Fellow Catharine Young explains a novel approach she thinks can fix the problems.